Flavinkins (@Flavinkins)
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https://zenodo.org/record/7005332 https://gab.com/Flavinkins/posts/108825099943844332 https://gab.com/Flavinkins/posts/108725195810150843 How could you claim “two spillovers” for SARS-CoV-2 if https://archive.ph/JVFuc positions 8782 and 28144 were found to be so unstable that they were observed to mutate within the same human host? And how could “multiple polytomies” indicate “double zoonosis” when it literally appear in every superspreading cluster and major variant of SARS-CoV-2 today? https://gab.com/Flavinkins/posts/109016556387587166 https://gab.com/Flavinkins/posts/109179292343046033 Your simulation is wrong if what you claim to be extremely unlikely, happens all the time. https://gab.com/Flavinkins/posts/108956120173554636 https://gab.com/Flavinkins/posts/108974982120327267 https://gab.com/Flavinkins/posts/108983088984087090 https://gab.com/Flavinkins/posts/108941081553382213 It just happened that the phylogenetic tree topology of SARS-CoV-2 once you begin to look past 14/02/2020, resemble perfectly that of measles. Another virus with superspreading, one that appears only in humans. https://gab.com/Flavinkins/posts/109025416744564920 https://gab.com/Flavinkins/posts/108860074766577121 https://gab.com/Flavinkins/posts/108922841820898119 https://gab.com/Flavinkins/posts/108763931290402313 Here is why you get the polytomy at lineage B. (28144T and 8782C confers greater disease severity and higher transmissibility, which is also why lineage A went extinct) https://gab.com/Flavinkins/posts/108996982333862686 https://gab.com/Flavinkins/posts/108869387343860968 (Also hint: http://nature.com/articles/s41467-021-26884-7 https://archive.ph/ejdiJ one of the earliest superspreading events of lineage B after the Huanan seafood market superspreading event originated from an infected brain—such compartments accelerate viral evolution and skews the lineage B MRCA backward as the result). Also, quasispecies should not be ignored when it comes to the modeling of phylogenetics and phylodynamics of RNA viruses. https://gab.com/Flavinkins/posts/108861410320430025 https://gab.com/Flavinkins/posts/108864606801240300